Help! What Are the Side Effects of Prednisilone? (Vet Answered)
This question has been answered by a vet
Veterinarian & Animal Behaviorist
With nearly two decades in veterinary medicine, Dr. Paola brings hands-on experience across multiple species. A graduate of the University of Guadalajara, she specializes in preventive care, animal welfare, and positive reinforcement training.
The Question
“My kitty Dusty is on Prednisilone. Is heavy breathing a side effect? – Laurie
Quick Info about Dusty
Hi Laurie. Prednisolone is a corticosteroid that can have various effects on a cat’s body, but heavy breathing is not a common or expected side effect. While mild panting can occasionally occur, especially in moments of stress or excitement, persistent or labored breathing is a red flag that should not be ignored.
Heavy breathing in a cat taking Prednisolone could indicate an underlying issue such as fluid retention, high blood pressure, or an underlying heart condition that may have been unmasked by the steroid. In some cases, corticosteroids can contribute to respiratory complications, particularly if there is an undiagnosed heart condition or an infection.
Additionally, steroids suppress the immune system, which can allow infections (especially respiratory infections) to worsen. If Dusty had a mild underlying respiratory issue, the steroid may weaken his ability to fight off infections, leading to increased congestion, inflammation, or difficulty breathing.
Because breathing problems in cats are always serious, I strongly recommend having Dusty checked by a vet as soon as possible. If the breathing is rapid, labored, or Dusty is open-mouth breathing, this should be treated as an emergency.